Artificial Biology, Molecular Evolution, Astrobiology

Our research focuses on reconstructing molecular time machines to explore and attempt to rebuild lost histories. We tackle challenging questions to understand life’s fundamental innovations. Our approach enables the reconstruction of biomolecule-scale macroevolutionary trends that span billions of years of Earth history and is a fundamentally new methodology with which to study the origins and early evolution of life.


Publication (Feb 2019): How to resurrect ancestral proteins as proxies for ancient biogeochemistry.

Preprint (June 2019): Reconstructed ancient nitrogenases suggest Mo-specific ancestry.

New article (October 2019) how geochemical organization preceded polymeric information in RNA world.


Latest preprint (December 2019): Evolutionary stalling in the optimization of the translation machinery.

Looking for the origins of life using synthetic biology: an interview with Betül Kaçar

by PLoS Blogs. 


Exploring early Earth by using DNA as a fossil, Betül talks to Marc Kaufman, NASA Many Worlds.

John Templeton Foundation Researcher Profile: Q&A: Five Questions with Betül Kaçar


Brooke Carruthers explores the potential of space sciences education for developing critical thinking and inspiring students Read More >>>

See why Cathryn Sephus loves studying the scales of life - from minuscule to maximum, from microscope to telescope Read More >>>


© 2020 Kacar Research Group

University of Arizona, 1007 E Lowell St, Tucson, AZ 85719

  • Twitter - Black Circle