Synthetic Biology, Molecular Evolution, Astrobiology

Our research focuses on reconstructing molecular time machines as a way to explore and attempt to rebuild lost histories. We use tools drawn from synthetic biology, molecular biology and evolutionary biology to tackle challenging questions in life sciences that will allow us understand life’s fundamental innovations. We hope to reveal underlying molecular mechanisms that are directly and indirectly responsible for maintaining conditions of habitability on our planet’s surface.


New publication: How to resurrect ancestral proteins as proxies for ancient biogeochemistry. 

New preprint: Reconstructed ancient nitrogenases suggest Mo-specific ancestry.

Looking for the origins of life using synthetic biology: an interview with Betul Kacar

by PLoS Blogs. 

Graduate student Cathryn Sephus receives WAESO grant supported by the Louis Stokes Alliance program of the National Science Foundation. Congrats Cathryn!

Exploring Early Earth by Using DNA As A Fossil, Betul talks to Marc Kaufman of Many Worlds Column.


New article outlines how geochemical organization preceded polymeric information in RNA world. Read More >>>

Evrim Fer joins the laboratory as a Genetics GIDP graduate student. Welcome, Evrim!


© 2019 Kacar Research Group

University of Arizona, 1007 E Lowell St, Tucson, AZ 85719

  • Twitter - Black Circle